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Oxygen and Venous O2 sampling

Lisa Nagy
Feb 06, 2008

 The use of O2 in the Environmental Patient:


First test the Venous O2 with a VBG, no tourniquet at the hospital to see if O2 is indicated in the first place.


    Tissue hypoxia from endothelial damage to capillaries which leads to swelling of the endothelia and does not permit O2 to get across the membrane to the tissue.   This leads to muscle, heart, brain  hypoxia which leads to  (in my case) mitochondrial damage from anoxia at the severest end of the spectrum.  My arms were blue and lactates were high  (Lactate /Pyruvate ratio 65 which is very high).  We measure venous 02 which you can do at any hospital lab -- anticubital vein no tourniquet-- I just discuss it with the lab director before I send patients to smooth the inevitably ruffled feathers of the tech who has to draw it and put in in a green tube for respiratory or an ABG syringe. 

    Normal is 20 to 25 and many patients who think they are fine are 32 to 36.  But you can see that their brain function and memory aren't great.  the sicker patients are in the 40's and they have chronic fatigue and may sweat on exertion and looked spaced out.   Keeping in mind arterial PO2 is about 100, you will see how poor I was when I tell you that my venous O2 was 75 when I was in LA!  Those in the 70's are the highest recorded and I only know of 1 besides mine.

    The treatment is 18 days or more of O2 for 2 hours a day at 5 liters  with a set up (mask and tubing from Dallas).  The Venous O2 becomes about 20-25 after 10 to 20 days and depending on the ongoing exposure can stay there for 6 months to a year -- it is quite incredible. Some need to continue O2 for a long time, it helps the dysautonomia significantly as well as reactions to incitants. A great article on how Hyperbaric Oxygen effects nitric Oxide prodcution was also just published.

    This I am sure is one of the reasons the patients appear  to have such bad cognitive and behavioral change  -- lack of oxygen to the brain.  Low cortisol and increased adrenaline secretion are the other factors that we experience.   So some is endocrine, neurotransmitter and nutritional imbalance, direct toxic effects from an exposure (mercury, mold, pesticide or whatever) and the rest is hypoxia. 

214 361 9515 The Foundation Store in Dallas - for these four things(about 125.00).

Ask for Tygon Tubing 8 -10 feet or more for two pieces total.

Humidifcation bottle

Porclean (or aluminum (if have a beard)) mask

Rebreathing Reservoir (cellophane bag in a little wood frame to make flow high enough when you make a seal with the mask and inhale ).

What to ask to be written on the order or prescription for your Venous Oxygen test which can only be done at the hospital or perhaps your environmental doctor's office.

Venous Blood Gas:  drawn from  anticubital vein without application of tourniquet. 

Blood to be placed into ABG syringe or Green top tube and transported for analysis to respiratory or wherever ABG machine is located.

Your donations help:

Lisa Nagy M. D.
Tel: 508 693 1300
email: VPM@nagy1.com

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